This study examines the transformative potential of Artificial Intelligence (AI) in development communication teaching and practice. It explores the opportunities and challenges associated with AI integration, emphasizing the need for a nuanced approach that prioritizes ethical considerations and responsible implementation. A quantitative cross-sectional survey of 50 development communication educators and practitioners in Nigeria revealed a strong consensus on AI’s potential to enhance content creation, data analysis, and audience engagement. However, concerns were raised regarding algorithmic biases, the digital divide, and the need for critical media literacy. The study underscores the importance of addressing these challenges through fairness-aware algorithms, expanded access to technology and digital literacy training, and the development of ethical guidelines and regulatory frameworks. By navigating the complexities of AI integration, development communication can harness its power to drive positive social change while mitigating potential risks. This research contributes to the ongoing discourse on AI’s role in development communication, offering insights for educators, practitioners, and policymakers to navigate this evolving landscape responsibly and effectively. Keywords: Artificial intelligence, Development communication, Opportunities, Challenges, Social change, Inclusive development